Non-steroidal Anti-Inflammatory Drugs and the Rate of Fracture Healing in Rats

Item

Title

Non-steroidal Anti-Inflammatory Drugs and the Rate of Fracture Healing in Rats

Description

L. P. Young Student Center, West Dining and Flag Room

Non-steroidal anti-inflammatory drugs (NSAIDs) are a treatment for alleviation of pain and inflammation following a bone fracture. The purpose of this review was to determine if NSAIDs effect the rate of bone healing and recovery rate. This literature review used articles found on EbscoHost, Medline, PubMed, Google Scholar. Key words used were bone healing, fracture, Non-steroidal anti-inflammatory drugs. All studies reviewed were conducted on rats. Nine of the eleven literature reviews concluded that NSAIDs demonstrated a decreased rate of bone healing. Five articles reviewed were clinical trials (RCT). All RCTs discovered bone healing decreased when compared to a control group. Two of five articles found NSAIDs delayed the progression of healing due to slow replacement of cartilage. The researchers concluded that NSAIDs may be a risk factor for bone healing. Patients with fractures should avoid NSAIDs and should use an alternative medication for pain control.

Wanda Swiger

Contributor

Keene State College

Creator

Paige Tuttle

Kelsey Cognetta

Date

2016-04-09

Identifier

https://commons.keene.edu/s/KSCArchive/item/21062

Subject

Athletic Training

Type

Presentation

Rights

http://rightsstatements.org/vocab/InC/1.0/

Item sets

AEC 2016 School of Sciences and Social Sciences

Site pages

School of Sciences and Social Sciences