How to Efficiently Synthesize A Macrocycle in a Laboratory Environment: A Summer Undergraduate Research Fellowship (SURF) Supported Chemical Research Project

A Summer Undergraduate Research Fellowship (SURF) supported chemical research with a goal of learning to imitate one of nature's secrets: how to efficiently synthesize a macrocycle in a laboratory environment. Macrocycles contain large rings of atoms that can be created by linking different atoms together. These are challenging to make because smaller rings or chains of atoms are preferred. Nature uses proteins and other cellular machinery to steer the arrangement of atoms into a large ring, thereby avoiding the preferred small rings and chains. This research aims to use a specific molecular template that favors the linking of two ends of the molecular chain into a ring. Many macrocycles have useful properties like their antibacterial action, and creating the foundation in the preparation of macrocycles would enable further investigation of these structures. Specific topics covered will include the goals of this research project and the effort in learning nature?s secrets.

Paul Baures

Keene State College

Kayla E. Carta

2017-10-11

http://hdl.handle.net/20.500.12088/8099

Chemistry

Presentation

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